1447 year 29 сафар | 2025 year 23 august, saturday
Regions:
Тошкент
ЎЗ UZ RU EN
Articles

Green tea compound helps antibiotic kill resistant bacteria

12:23 / 24.09.2019 948 Reading mode + -

According to a new study, a molecule found in high quantities in green tea can boost the efficacy of a common antibiotic. A team of international researchers discovered that administering the natural compound in combination with the antibiotic effectively killed a notoriously antibiotic resistant bacteria.

Epigallocatechin (EGCG) has been the focus of a great deal of research in recent years. It is found in extraordinarily high levels in green tea and many scientists suspect it could be responsible for some of the common health benefits linked to the beverage.

This new research set out to explore whether EGCG could enhance the effect of antibiotics in treating particularly strong bacterial pathogens. The study focused on Pseudomonas aeruginosa, a dangerous pathogen resistant to many antibiotics that is becoming a major concern in many hospitals around the world.

The study revealed EGCG, administered in synergy with an antibiotic called aztreonam, could effectively kill Pseudomonas aeruginosa in laboratory tests, and in live organism tests using moth larvae.

“Antimicrobial resistance (AMR) is a serious threat to global public health,” explains lead author Jonathan Betts. “Without effective antibiotics, the success of medical treatments will be compromised. We urgently need to develop novel antibiotics in the fight against AMR. Natural products such as EGCG, used in combination with currently licensed antibiotics, may be a way of improving their effectiveness and clinically useful lifespan.”

It is currently unclear exactly how EGCG enhances the efficacy of aztreonam. The researchers hypothesize the natural compound may increase antibiotic permeability in the bacteria but further work is needed to home in on the specific mechanism at play.

“The World Health Organization has listed antibiotic resistant Pseudomonas aeruginosa as a critical threat to human health,” says Roberto La Ragione, another author on the new study. “We have shown that we can successfully eliminate such threats with the use of natural products, in combination with antibiotics already in use. Further development of these alternatives to antibiotics may allow them to be used in clinical settings in the future.”

Before green tea drinkers get too excited about this new discovery it's important to note it isn’t clear what concentration of EGCG is necessary to generate these beneficial results. While a great deal of prior research has uncovered medical benefits to the green tea compound, it often needs to be administered in high volumes to achieve these positive effects.

A 2018 study did find that EGCG can result in liver toxicity and the FDA has frequently targeted a number of EGCG dietary supplement manufacturers for misleading promotional materials. The compound is also known to be poorly absorbed when consumed orally, so it may need to be modified before it can become an effective human medicine.

Related articles
One day the Messenger of Allah peace be upon him was sitting near the hill of Safa. Abu Jahl passing by insulted him. Muhammad peace be upon him did not say anything to him. The slave girl, who was released by Abdullah ibn Judaposan radiallahu anhum, reported this to Hamza radiallahu anhu, the more...

2014 13:42 / 18.02.2020
In a message posted on AlAzhar`s social media page, the center said the Quranic advice for such crises is summarized into two issues strengthening the faith in Allah and thanking Him for the Divine blessings.Referring to verse 147 of Surah anNisa, aposaposWhy should Allah punish you if you give more...

838 10:01 / 07.04.2020
Believing in the Prophets of Allah is also a very wise action. It is a great honor for mankind that Allah has chosen His prophet from among men. The chain silsila of prophets from Adam to Muhammad peace be upon him is the chain of honor for mankind. The Prophets peace be upon them are the persons more...

983 10:16 / 09.04.2020
Allah Almighty says in the Quran about the Prophet peace be upon himquotAnd you are of a great moral character.quot Surah alQalam, 4Yes, he was adorned with all kinds of good qualities. One of such beautiful behavior is to greet both adults and children.Anas ibn Malik radiallahu anhu reportedThe more...

1164 17:38 / 17.06.2020
Tazkiya
HADITH OF THE DAY
Anas ibn Malik radiallahu anhu reported Allahaposs Messenger peace be upon him having said on the day of Nahr SacrificeHe who slaughtered the animal as a sacrifice before the aposId prayer, should repeat it i. e. offer another animal. Thereupon a person stood up and said Messenger of Allah, that is more...